This paper does a brief introduction on B2B2C e-commerce, network structure, network relationship and the growth of e-commerce firm. Then it sets a theoretical framework and uses case study to explore the impact of firm’s network on the growth of B2B2C e-commerce firms involving retail, travel and shoes industries. The result of case studies indicates that firm’s network structure and firm’s growth, firm’s network relationship and firm’s growth, firm’s network capabilities and firm’s growth all have clear positive correlations. Then this paper puts forward relevant hypotheses and does pretest to ensure the effectiveness of questionnaire. Finally, it discusses the limitations and points out future research direction.