The adoption and use of digital technologies have been a growing area of research focus in recent years. Despite the popularity in developed countries, digital technology adoption amongst SMEs in developing countries, e.g. Nigeria, is still relatively low. Such low adoption hinders the digital transformation of SMEs in the developing countries, and the low level of adoption is often the result of the low level of digital business readiness. Therefore, this paper proposes the digital business readiness assessment framework (DBRAF) based on Socio-Technical Systems (STS), Unified Theory of Acceptance and Use of Technology (UTAUT2), Organisational Semiotics (OS) and Enterprise Architecture (EA). The DBRAF is designed to understand and examine the enablers and barriers of digital business adoption for SMEs in developing countries. A pilot study, based on a pilot study in fashion retail SMEs in Lagos, was conducted to test the validity of the proposed framework. The DBRAF aims to assist fashion retail SMEs to identify the specific areas that they need to be address in order to reach the desired level of digital business readiness.