Computerized Physician Order Entry (CPOE) represents a monumental step forward for healthcare organizations because it embodies a shift from traditional, paper-based care coordination activities to automation of the order entry processes. Although many hospitals have recognized the medical, fiscal, and overall strategic advantages associated with investing in such technology, to date very few hospitals have implemented automated order entry systems. This study seeks to lay the framework for a new model of technology acceptance; one that incorporates the unique features of physicians and physician extenders, and the complex environments in which they work. Through the use of semi-structured interviews, direct observation, field notes, and archival record analysis, a longitudinal, instrumental case study will be undertaken, which will track technology acceptance among practitioners with varying specializations. Of particular interest is the degree to which organizational culture, the work values of achievement, autonomy, recognition and patient relationships, and the values of justice, beneficence, non-malfeasance, and autonomy - essential components of the physician’s code of ethics - may be facilitators of technology acceptance.