The study aims to examine factors that are influencing knowledge management success in one of the leading company in oil and gas industry in Saudi Arabia. It equally evaluates and validates a new proposed framework Information System Technology Acceptance Model (ISTAM) by combining two previously validated information system questionnaires. Data were collected from 401 employees of an oil and gas company in Saudi Arabia by adopting simple random sampling technique. Confirmatory factor analysis was used to measure and validate the hypothesized model while Structural Equation Modeling (SEM) and AMOS were used to test the highlighted hypothesis. The major findings which can be deduced from the overall results of the study is that, IS theories’ underline’s construct and components fitted well in overcoming knowledge management success challenges. This result practically states that, IS theories as embedded in the KM model can suitably bring about knowledge management success in corporate organization.