Overall, IS research provides powerful tools that allow understanding individual acceptance and use of systems. However, researchers are increasingly concerned that it provided very little indications about how user adaptive strategies to IT influence IT adoption and success. Drawing on the Coping Model of User Adaptation (CMUA) (Beaudry and Pinsonneault 2005) and on the Information Systems Success Model (ISM) (DeLone and McLean 2003), we elaborate a research model for gaining further knowledge into the influence of user adaptive strategies on IS success. The four generic adaptive strategies of CMUA are posited to moderate the influences of information and system quality on intention to use and user satisfaction. A longitudinal quantitative research design is then presented. It deals with individuals adaptation to new Cloud Computing IT in a large, 6,500 employee French corporation. Expected contributions for research and practice are presented.