Unintentionally, the growth of health websites deepened health disparities between population subgroup as it considers the perception of some sub-populations and ignore the needs of others when designing health websites. This paper presents a study that aims onto considering the perception of the African American in identifying the quality attributes of health websites. Based on focus group research and two-round factor analysis, findings indicate that quality of health websites is a function of dimensions of Aesthetic Design’, ‘Website Usability’, ‘Information Quality’, ‘Information Architecture’, ‘Responsiveness’, ‘Trust’, ‘Identity’, ‘Appropriateness to Culture’, and ‘Learnability’. The paper provides useful messages for website designers, website content mangers, usability practitioners, and web-based healthcare program managers. Also, theoretical implications and limitation of the study are presented.