Organizations are increasingly concerned with the continuous reassessment and redesign of their products, processes, and business models to remain competitive in uncertain environments. Thereby, mental models, routines, and behaviors of individuals and entire organizations need to be updated to fit changing demands and environmental factors. 'Unlearning' is a promising approach to achieve this because it allows knowledge to be refined and adapted to novel situations. Unlearning established ways of thinking and doing effectively poses, however, several challenges that could be mitigated by an appropriate tool support. By following a qualitative systematic review of literature from Information Systems and adjacent disciplines, we identified and synthesized existing tools and guidance to assist individuals, teams, and organizations in unlearning. With our study, we contribute to an integrated overview of practical support for unlearning based on a sample of 41 papers as well as useful guidance for practitioners, designers, and researchers.