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The pursuit of physical and mental integrity is a fundamental instinct that has accompanied humankind since the dawn of time. Based on the digitalization modern medicine nowadays no longer has only access to self-collected information, but to information from almost all areas of the patients’ lives, which makes it possible to create a digital representation of them. This digital twin opens completely new and until now unthinkable possibilities, not only in the field of monitoring and prevention, moreover it is the key to personalized medicine. However, unlike other domains, the healthcare sector lacks a structured approach to exploit this paradigm. Against this background, based on a systematic literature review and the methodological approach of Nickerson et al. (2013), the paper presents the essential dimension as well as characteristics of digital twins healthcare applications as a taxonomy that has been evaluated against 100 healthcare applications



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