It is generally acknowledged that successful exploitation of technology for competitive advantage requires the strategic alignment of organisational goals with information systems strategies. Globalisation and increasing cross-cultural and multi-national deployment of information systems makes it imperative to understand how differences in culture at the national level impact organisational efforts to achieve strategic alignment. This paper explores whether, where and to what extent, national culture dimensions impacts strategic alignment as part of an on-going cross-cultural research. It discusses the implications and outlines the trajectory for future research.