An adoption of appropriate technology can lead the company to greater business competency, improve its business performance, and ensure it retains its competitive advantages. Despite this awareness, many SME in the developing countries in the Middle East have yet to fully embrace this adoption of ecommerce in the running of their business. The problem in this research is to identify and bring together in one framework the appropriate issues, variables, components and concepts that need to be addressed to encourage, motivate and enable SME‟s in Middle Eastern countries to adopt electronic commerce technology in the running of their businesses. The aim of this study is to develop a comprehensive research framework called Electronic Commerce Technology Acceptance (ECTA) framework, which is utilised for discovering the factors affecting the adoption of e-commerce innovation and to apply this framework for empirically testing the adoption of e-commerce application by SMEs in Middle Eastern Countries. This empirical study was conducted through survey research and the sample was drawn by means of systematic sampling technique. The empirical data were collected by using self-administrated questionnaires and semi-structured interviews. The data analysis is based on 400 Jordanian SMEs; also data analysis was based on multivariate statistical techniques encompassing multiple linear regression, simple linear regression, and one-way ANOVA. The findings from this research show that the ECTA framework is beneficial to both governmental and private sectors who intend to accelerate the adoption rate of electronic commerce implementations and their relevant components among SMEs in Jordan.