This panel is related to the education for the practice of IS Leadership roles in Digital Transformation within a given framework of Digital Strategy and Enterprise Architecture. As members of education and collaborative research teams that have been studying and teaching the correct direction of IS leadership roles in Digital Transformation in global enterprises while applying Digital Enterprise Architecture (DEA) Framework – the “Adaptive Integrated Digital Architecture Framework (AIDAF)” with DEA Cube Framework, because the above roles have difficulties and a number of risks especially during Digital Transformation. Thus, the panelists will discuss and debate the theory, practice, and extent of educator’s precise guidance and considerations when performing the aforementioned leadership roles and studying their accurate directions during Digital Transformation. This panel of senior IS educators and researchers with industry experience will discuss the challenges and effectiveness of “Architecture for Digital Transformation Toward IS Leadership Education” for the new era of Digital IT.