The objectives of this paper are to report on the development of a program in Clinical and Healthcare Informatics and to assess its impact in terms of (1) the importance of each of the competencies for successful job performance; and (2) the effectiveness of the program in enabling participants to achieve these competencies. The results will be of value in the design and implementation of similar programs for clinical and healthcare professionals because the competencies that are most relevant to successful job performance may become the building blocks for future program development.