In this working paper, we propose that an organization is a living organism that generates energy to achieve certain outcomes. We propose that the relationship between the inputs (individual and group use of information systems) and the outputs (strategic alignment and competitive advantage) of a system (an organization) depends on the basic principles of quantum mechanics. Specifically, we connect the neuroscience research that addresses qualia (individual) and quale (group) to the Management Information Systems (MIS) research. In this paper, we proffer our research objective, discuss our constructs, and present our interview process and survey items that we plan to conduct and administer.