This paper explores the need for integrating effective information systems management into hospital strategic planning and suggests a methodology for constructing a strategic information system (SIS) development framework that is flexible enough to permit a hospital to adjust its strategies to environmental changes and to stay on course with its vision. This SIS architecture utilizes a systems perspective of strategic decision making within a hospital in two phases. Organizational analysis examines the hospital’s current position within the environment and the development of the hospital’s vision and goals. Strategic Information Systems development includes SIS goals assessment, strategic information requirements analysis (SIRA) and SIS implementation planning.