Contemporary knowledge workers face information security-related stress and often struggle with responding to security threats. Employees deal with stress using different coping strategies. Some adopt avoidance coping mode to dissociate themselves with stress while some adopt approach coping mode to actively solve problems. We propose that being mindful on countermeasures of information security threats can ease stress and the negative impacts caused by stress. In addition, we also hypothesize the moderating effect of mindfulness on the relationships between security-related stress and two coping modes.