This study explores knowledge management practices in a Malaysian public healthcare organization. Knowledge management has gained much attention not only from business enterprises but also in other fields such as education, urban planning and development, governance as well as healthcare and has allowed for an enterprise-wide structure to be put in place to promote efficient and effective decision-making process. As a result, many organizations are now more serious about managing knowledge and embracing the concepts associated with knowledge management to remain competitive, or even to survive. Healthcare practitioners are a knowledge-based community that depend heavily on knowledge management activities. However, little study has explored the processes used by practitioners in managing knowledge as one of the intellectual assets of the business. Hence, this paper focuses on knowledge management practices among medical staffs particularly on how they build their knowledge schemes, scan for knowledge and use knowledge in their organizations. The paper's primary goal is to examine how medical staffs employ knowledge management processes to the benefit of their clinical routines and ultimately to develop a knowledge management model for disease management. Theoretically, this study aims to provide a model that will add to the existing models on knowledge management processes; extend the initial model used in this study; examine the contribution of different knowledge workers to the model as well as guide practitioners in understanding, acquiring and applying knowledge effectively. By adopting an interpretive case study approach, two distinct roles of medical staffs were selected to reflect how knowledge management process is being practiced in their organization.