Digitalization of regional public health information is an irreversible trend in the course of China's social development. This is also one of the key tasks to reform China's medicine and public health system. To learn more about the influence of using information technology for medical personnel and hospital performance, this study reviews in the personal perspective to know more about the sustainable action of using IT in hospitals based on the Theory of Planned Bahavior. We proposed a research model which expanded TPB and tested it based on 278 valid data collected from employees in a large-scale hospital in Anhui Province, East China. The results of study reveal: 1.We verified TPB in the Chinese context and found that attitude and subjective norm not only have a directly influence on behavioral intention, but also can influence the use behavior.2.The habit of using IT of medical personnel has a directly influence on the attitude of using IT, and it also has significant influence on the behavioral intention. Our research model discovered the relationship between subjective factors of IT users’ and their behaviour. The founding of this study not only can provide references regarding the direction of public hospitals reform in China for decision makers of hospitals, but also is very helpful for management teams in hospitals to adopt more rational management measures for better IT use among medical personnel, and better hospital performance.