The purpose of this study was to examine which Business majors are currently being selected by new Business students and, more particularly, to examine why students are not majoring in Information Systems (IS). Students in an entry-level Business class responded that they were more knowledgeable about careers in Management, Marketing, Accounting, and Finance than they were about careers in Information Systems. These Business students indicated they mostly lack knowledge of and are unaware of the Information Systems major and associated occupations. Furthermore, their knowledge void leads them to perceive IS negatively in regards to desirable payoffs such as job availability, pay and benefits, promotion opportunities, and job security and longevity.