The maritime industry is made up of a complex ecosystem consisting of many actors. Digitalization has presented solutions to many earlier challenges faced by maritime professionals and has also led to new opportunities for improving maritime safety, vessel coordination, navigation, control and communication. However, with these technological advances, have come new known and unknowable cyber-threats and cyber-security challenges to an industry that is already renowned for being one of the sectors most targeted by pirates and criminals. This study aims to investigate whether (and how) maritime safety culture and cyber-security factors (hygiene) impact on-board ship safety measured through maritime professionals’ resilience capabilities, decision-making performance, and collaborative performance. The empirical findings of our quantitative study found that maritime professionals working onboard digitalised ships with improved awareness of cyber-security and the safety culture improved the overall resilience capabilities of ships and that onboard decision-making impacted collaboration with stakeholders.