In this paper we aim to develop a patient centered perspective that puts at the centre of our focus patient practices and their appropriation of medical information, prescribed use of drugs and of health-care technology. Within this frame, we will initially discuss evidence from a qualitative case study on the role of community pharmacists in patients dealing with their problems. In line with the 2.0 revolution, we then suggest a technological architecture based on patient generated content and their health social networking – as many Health 2.0 platforms already do – that focuses on local relation and take into account the empirically assessed role of pharmacists and investing them with an interesting local task. Future challenges and initial reflections of the proposed approach will be discussed at the end.