We examined the impact of users’ information privacy concerns on information systems (IS) effectiveness in organizations. Specifically, we investigated system users’ psychological mechanisms that may involve in the relationship between privacy concerns and IS effectiveness (i.e., perceived usefulness and IS satisfaction) via information systems reactance (ISR) on systems and procedural justice (PJ) toward their Information systems. The results supported our hypotheses in that: (1) Privacy concerns were negatively related to system users’ perceived usefulness and IS satisfaction, (2) Both ISR and PJ of the system users mediated the relationships between privacy concerns and IS effectiveness. We discuss the implications of the findings for theory and practice, and their limitations and the directions that future research in this area might explore.