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Despite the proliferation of mergers and acquisitions (M&As) for last few decades, lots of M&As have failed to fulfil planned objectives and to create synergy. Many researchers pointed out the failure of post-merger information systems (IS) integration as one of critical causes for M&A failure. This study, based on organizational justice theory (OJT), proposes a research model to identify the impact of IS employees’ perceived fairness on their organizational commitment during post-merger integration stage. In addition, the relationship between those variables and organizational trust and job insecurity is also examined. We expect the results of this study can contribute to provide some guidelines for the firms that is now integrating IS systems after M&A or considering M&A in the future.