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The paper describes a new framework for multidisciplinary concept evolution (MCE). The impetus for systematizing the research concepts was a practical need to facilitate successful communication between different disciplines. The main benefit of the framework is that it aids the complex and dynamic process of conceptualization by highlighting abstraction, generalization, and ontology engineering as practical methods to implement concept evolution. One application of the framework is in solving complex business-related problems. The MCE framework can be utilized not only by researchers but also by other community stakeholders. Applying the framework to scientific disciplines may bring additional value to research as well as benefits to practical development endeavors.