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As seen in the wide range of researches, the lack of a proper and profitable business model is an important factor in companies’ failure and in the use of Internet and e-business. In this paper we want to determine the best (or portfolio of) e-business models for each organization by which they can use Internet and information technologies in the optimal manner in their business. To do so, we will consider strategies, organizational and environmental conditions of each organization and determine the best e-business models in the base of these conditions. So two steps appraisal process be introduced, that can improve the earlier frameworks and remove their disadvantages and also it can assist managers in the choice phase of decision-making.