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The objective of the present contribution is to present the results of an explorative survey in the field of E-Business conducted with German enterprises at the end of the year 2003. The survey aimed to convey a picture of the present stage as well the future trends of E-Business in the German entrepreneurial world. An analysis of the present and future developments of E-Business as well as of the related organisational, technical and human implications for enterprises will be presented. Limitations and open challenges of research as well as the planned further work will be eventually discussed.