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It has been widely recognized that RFID related technologies will greatly improve the visibility, the efficiency and the collaboration of industry supply chain. In this new “product driven“ supply chain scenario, manufacturer, supplier, and third party share and coordinate the use of diverse resources in distributed “virtual organizations”. It challenges the security issues, which demand new technical approaches. In collaboration with researchers in Auto-ID Labs China, we have developed a service-oriented framework based on CA and Web Services, which supports inexpensive mediation of product information among rapidly evolving, heterogeneous information sources. Our architecture defines a user-driven security model that allows users to create entities and policy domains within virtual organizations. We emphasize that standard Web Services tools and software provide both stateless and stateful forms of secured communication.