Since the dawn of evolutionary technological civilisation, analytics has promised to revolutionise healthcare and enable more efficient patient care delivery. However, after the applications of AI tools in healthcare, doctors and patients are no longer the sole players in the doctor-patient relationship. AI emerges as the third player, which creates unique opportunities in this relationship. By examining the impact of non-human actor-AI on the doctor-patient relationship and exploring the related concepts, such as human-AI augmentation and human-in-the-loop, valuable insights can be gained regarding the use of AI in healthcare. Following this background, based on a systematic literature review and the methodological approach of Lebovitz et al. (2022), this paper seeks to enhance the knowledge and expertise in healthcare by examining how AI tools shape and are shaped by the doctor-patient relationship when three players (AI, doctors, and patients) are present.