In recent years, e-collaboration systems have emerged as an essential enabler of communication and collaboration between enterprises. Current trends in the area of e-collaboration emphasize the importance of effective collaborative knowledge management support in e-collaboration systems. Our research aims at proposing an intelligent infrastructure for the reconciliation of knowledge management and e-collaboration systems. The objective of the paper is to introduce a conceptual framework for designing and building the new infrastructure that supports specific characteristics of collaborative knowledge management in e-collaboration systems. The paper articulates how this framework enables efficient knowledge exploration and exploitation, before concluding with implications and recommendations for future developments in this area.