Management of enterprise development refers to the complex task of transforming an enterprise from one state to another (desirable) state in a controlled manner. This paper presents a framework that enables the systematization of empirical as well as theoretical knowledge contributions relevant for management of enterprise development. The framework is validated theoretically as well as empirically. The framework has proved effective to systemize and relate this variety of issues and provide a tool for comprehensibility for practitioners trying to grasp the development situation in which they engage. The framework is a valid foundation for elaborating a knowledgebase supporting the management of enterprise and IS development in complex organisations.