This paper reports on findings into the benefits, challenges and success factors of electronic commerce in the Australian manufacturing industry among the top 500 Australian publicly listed companies. The paper investigates anticipated and identified challenges, benefits and success factors of electronic commerce, and possible relationships between them. The results showed that manufacturing industry encountered similar challenges, identified similar success factors and achieved similar benefits as the other sectors of Australian economy. Although this research addresses well-established business enterprises in Australia, the nature of electronic commerce is such that it is global and the findings should be applicable to large organizations over a much wider scope. Some of the findings could as well be applicable to small and medium size businesses/organizations.