This study began in 2013 through investigation of previous Information Technology Governance (ITG) relationships, in which theoretical evidence was identified to support the perception that the effectiveness of ITG is a result of the alignment between the principles, objectives and mechanisms of ITG. From its partial results, it is possible to highlight the definition of a conceptual model proposed by a Focus Group, in which this Group identified the perspective of IT Governance effectiveness as the one used. The aim of this research is to confirm the relationships between these constructs and to identify the existence of moderation of these relationships through the dimensions of organizational culture. The study is a descriptive exploratory research by nature involving different methodological strategies, working mainly with structural equation modelling.