This article develops the Digital Ecosystem Technology Transformation (DETT) framework for explaining technology-based transformation of digital ecosystems. In digital ecosystems, the fusion relation between business and technology means that the decision of technical compatibility of the offering is also the decision of how to position the firm relative to the coopetive relations that characterize business ecosystems. The DETT framework depicts ecosystem transformation as distributed and emergent from micro-, meso-, and macro-level coopetition, based on interrelated business and technology ecosystems positioning. As such, the DETT framework consists an alternative to the existing explanations of digital ecosystem transformation as the rational management of one central actor balancing ecosystem tensions. We illustrate the use of the framework by a case study of technology-based transformation in the digital payment ecosystem.