The aim of this study was to understand which factors hinder and facilitate the implementation of 4.0 technologies in health systems.Thus, to answer the core question of this study, we opted for a descriptive exploratory study with a qualitative approach, with semi-structured interviews being carried out with national and international personalities in the health sector and stakeholders in the health sector, in order to have a knowledge of their perception on the subject of the study in question.The results of our study suggested that the implementation of 4.0 technologies in health systems has as hindering factors: lack of funding, lack of qualified human resources, the current structure of health systems and resistance to change by professionals and patients and as facilitating factors: cost reduction and interoperability policies in health systems.