The main aim of this study is to review the literature relating to the factors that contribute to the business digital divide. A systematic literature review was conducted using two databases (Scopus and Web of Science). A total of 28 articles were selected and analyzed. The selected studies are conducted in various developing and developed countries, including all firm sizes and different sectors, and cover several different digital technologies. Identified factors determining the business digital divide are categorized as technological, organizational, and environmental factors. The discussion and the potentials for further research are also presented.