Psychologists started using information technologies, including Videoconference as new space for psychotherapy sessions. The technology role in building the relationship among psychologists and patients is still underexplored. Regardless of technology improvements, the Videoconference communication among therapists and patients can be affected by the features of audio and video quality, the lack of real and mutual gazes and the partial perception of body language. Applying a qualitative methodology based on semi-structured interviews, this study will focus on the role of technology in modulating messages, thoughts and emotions in the communication of a Videoconference therapy. The goal is to provide some understanding of how technology can contribute to the effectiveness of the therapy and enhance the understanding of the human communication by video. The implications of this study will be particularly relevant to detect the factors to be considered and improved in Videoconference Psychotherapy.