The agriculture industry has gained substantial productivity improvements and efficiencies due to the advancements in the information technologies (IT) landscape. While disparate knowledge in different disciplines is gaining substantial momentum, we need a consolidated interdisciplinary view of the salient findings of agricultural research to reach its full potential. Thus, information systems (IS) researchers have the potential to add value to this emerging theme. We reviewed 200 papers published on agriculture and IT from 2010 to 2016 and the prevailing literature demonstrates the value of this approach for advancing our understanding on agri-informatics. In this paper, we provide an overarching agri-informatics framework, possible theoretical lenses and research questions to encourage IS researchers to develop an effective cumulative tradition of research