The main aim of this paper is to provide a deep analysis on the research field of healthcare data analytics., as well as highlighting some of guidelines and gaps in previous studies. This study has focused on searching relevant papers about healthcare analytics by searching in seven popular databases such as google scholar and springer using specific keywords, in order to understand the healthcare topic and conduct our literature review. The paper has listed some data analytics tools and techniques that have been used to improve healthcare performance in many areas such as: medical operations, reports, decision making, and prediction and prevention system. Moreover, the systematic review has showed an interesting demographic of fields of publication, research approaches, as well as outlined some of the possible reasons and issues associated with healthcare data analytics, based on geographical distribution theme.