This paper proposes a new research program and presents a current analysis of the potential of health information systems (HIS) to improve primary care delivery in rural Indonesia. A new HIS will be implemented to facilitate patient centred primary care and to support the interactions and collaborations between three types of participants including the patient, their doctors and pharmacist in Malang, Indonesia. A tetradic relationship between the new HIS and three participants (patient, doctors, and pharmacist) is examined through the lens of the actor network theory (ANT) with a view to form a new healthcare service delivery model for primary care providers in Indonesia. Based on this model, a network of primary care providers would share the patient medical records (PMR) and provide collaborative care programs to promote healthy life styles, prevent diseases, and to manage chronic disease care more effectively and efficiently.