Radio Frequency Identification (RFID) enables a contact-free identification of objects either individually or in a bulk mode. The most salient promise of RFID in the realm of logistics is that it reduces object handling costs by automation. However the business potential of RFID reaches well beyond: By providing decision makers with a more detailed, precise, and timely information base, qualitative and indirect benefits can be realized and RFID can be turned into an enabler for farreaching process transformations. This paper derives a classification framework for RFID benefits that can be used for profiling benefits of envisioned RFID initiatives. The profiles are designed to support a targeted selection of benefit measurement approaches as well as for an identification of relevant gaps in the exploitation of the technology. Two complementary case studies are introduced and discussed to illustrate how resulting benefit profiles can be utilized.