Electronic commerce (EC) is emerging as a driving force in today’s economy. According to Forrester Research Institute (1997), the estimated sales in electronic commerce would rise from US$1 billion in 1995 to US$117 billion by the year 2006. EC activities are ranging from shopping to manufacturing (Shaw et al., 1997). This research is specifically focused on compatibility issues of operational strategies used in the manufacturing sector of electronic commerce. Electronic commerce is changing manufacturing systems from mass production to demand-driven and possibly customized, just-in-time manufacturing (Turban et al., 2000, Kalakota, R. et al., 1996). In electronic commerce, as product life cycle becomes shortened, high product quality becomes necessary for survival, markets become highly diversified and global, and continuous and unexpected change becomes the key factor for success. The ability to respond quickly and effectively to satisfy customers has become a defining characteristic of competitiveness for manufacturing companies in the electronic commerce era. Agile manufacturing is an emerging new manufacturing paradigm, which considers agility a key concept necessary to survive against competitors under an unexpectedly turbulent and changing environment (Goldman et al., 1995). Thus, agile manufacturing is a viable operational choice for the manufacturing companies in electronic commerce. As Shaw et al. (1997) point out that a key feature of electronic commerce research as a distinct discipline is its multidisciplinary perspective. This study is exploring electronic commerce research from both MIS and OM perspectives.