The proliferation of electronic commerce venues on the Web has dramatically expanded the reach of businesses. It is now much easier for a firm to deal directly not only with its customers, but with its entire supply chain. During the past several years, business-to-business transactions have become simpler, faster, and more accurate since the advent of electronic data interchange (EDI) and the explosive growth of information technology. The Internet is introducing yet another way for businesses to electronically conduct transactions in ways that are even more farreaching. Although this has led to some disintermediation at the brick-and-mortar level, new cybermediaries are being created to facilitate and validate the new business relationships. Internet auctions are being touted as one solution for at least some aspects of supply chain management. Attention so far has been primarily focused on the application of the technology. Although the technology facilitates the transactions and interactions of participants by increasing connectivity, other issues are also important in applying electronic auctions to supply chain management. The purpose of this paper is to identify and explore interdisciplinary issues potentially affecting the outcome of electronic business-to-business auctions in order to increase the awareness of Information Systems managers and auction participants so that effective implementation strategies can be developed.