In recent years, most major organizations have implemented enterprise systems from such vendors as SAP, Oracle, Peoplesoft, Baan, and J. D. Edwards. Historically, the emphasis of these systems has been on enhancing transaction-oriented business processes. Using the integrated, enterprise-wide knowledge store within enterprise systems for decision support is garnering an increased attention from enterprise system vendors and from third party software developers. Despite the recent interest in decision support from enterprise system practitioners, little research exists that connects enterprise systems to the field of decision support systems. This paper outlines the foundations of this connection along with an agenda to advance this line of research.