Based on the analysis of knowledge work’s structural characteristics, a relationship model between the knowledge work productivity and the corresponding procedure & standard was established. From the empirical research, this paper pointed that, the process of structuring for knowledge work does not necessarily lead to optimal productivity. The productivity shows a downward trend after the first rise with the structuring of knowledge work. At the same time, for the knowledge work positions with specific knowledge content, their productivity curve showed the first increase after lowering trend with the constant improvement of standardization; The higher the knowledge content of the positions have, the lower degree of standardization of its optimal productivity. This paper analyses the optimal productivity for the corresponding procedure and standard, as well as the innovational behavior potentially exists in the knowledge work with non-procedure and non-standard characteristic. This study puts forward a new perspective of scientific management and people-oriented management for the enterprise as well as provides a new theoretical perspective for the knowledge work productivity study.