The aim of this paper is to examine the factors influencing the adoption of human resource information system in the Saudi context. As few researches have been looked at the adoption of HRIS, Still, none of these studies has examined the adoption of such a system from the users’ perspective in general and Saudi Arabia in particular. This study has developed and tested technology acceptance model (TAM) that integrates service quality with perceived usefulness and perceived ease of use to investigate the factors affecting the users adoption of HRIS. The model was empirically tested using structure equation modelling by employing data collected from a survey of HRIS users. The findings and discussion presented in this study will help the Saudi organizations to understand the current status of their HRIS to improve it and benefit from it. This study provides guidelines for its implementation for theory and practices, limitations and future directions.