In this paper we consider transfer entropy and mutual information in terms of their application in the emerging highly interconnected and dynamic synthetic ecologies underpinned by the Cyber. We consider existing models relating to the management of learning and change within organizations and as they may relate to mutual information (MI) and transfer entropy (TE) within socio and info/techno settings, based upon a Mech-Organic perspective. A premise of this paper is that change is costly and that it needs to be seen through a social as well as an info/techno lens. We identify potential improvements to existing models and applications applied to the management of change by considering alternative models and how they may be applied collaboratively within a learning organization.