The successful extraction of business benefits from the use of information and communications technologies (ICT) has been a persistent problem. This study introduces the “Intelligent Exploiter” framework as a mechanism for improving the effective application of these technologies. This paper reports on evaluation of this framework within a large organization in health care – a sector with a history of resisting the adoption of integrated ICT systems. However, Western Healthcare (WHC) in the USA has received high praise for its ability to use ICT to help it provide better healthcare at lower costs. With this experience, senior executives of WHC have supported the efficacy of the Intelligent Exploiter framework.