Healthcare informatics involves different areas and activities like data collection, data analysis, and knowledge sharing among health care professionals. Healthcare Informatics scholars have been contending that the advancement in the discipline can enable healthcare professionals to provide better care to patients and the public. The current study goal is to identify the effectiveness of health informatics in improving clinical nursing practice from recent literature. We followed the systematic literature review by reviewing research papers published in the period between 2009 until 2019. The extracted data showed that there are four main themes of the nursing practices that are affected positively by the implementation of healthcare informatics. Namely, they are promoting quality of healthcare, improving electronic documentation of nursing practice, improving technological competencies and leadership practices, and improving clinical decision making. We discuss the findings and identify gaps to better direct future research in this area.

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