In this paper, we examine the design, execution, and subsequent performance between traditional Relational Database Management Systems (RDBMS) and modern NoSQL Database Systems, when implemented on a cloud server. While significant groundwork has been laid for this comparison, we will present two distinct scenarios for real-world comparison: one containing highly structured data, and one containing unstructured data. In addition to concerns of design, we will test our approaches to each model side-by-side in the same cloud environment.