Information systems are a critical factor in achieving supply chain agility in fluctuant markets. However, there has been limited research on identifying specific mechanisms on how information systems may affect supply chain agility. We address this gap by illustrating that IS complements supply chain agility on various operational dimensions, such as flexibility, responsiveness and dependability. We develop a conceptual model to explicate the significance of IS on several critical operational dimensions drawing examples from the context of the Chinese automotive supply chains.