The research reported in this paper elucidates the development, empirical validation and preliminary analysis of a model of technology acceptance by Australian occupational therapists. The study described involved the collection of quantitative and qualitative data through a national survey and a longitudinal multi-method case study within a communitybased healthcare organisation. The theoretical significance of this work is that it uses a thoroughly constructed research model, with potentially the largest sample size ever tested (2000+), to extend technology acceptance research into the health sector. Results provide support for the proposed model. This work reveals the complexity of the constructs and relationships that influence technology acceptance and highlights a need for reconceptualising current models. Results also demonstrate the importance of qualitative methodologies in information systems research. The significance and implications of the findings are discussed.